In the early phase (until the foundation and registration of the association), the German Federal Ministry of Education and Sciences appointed deputy managers who were in charge of Villa Vigoni:
- Dr. Robert Goroncy (1984-1986)
- Ulrich Podewils (1986-1987)
Former German Presidents:
- Ambassador Dr. Lothar Lahn (1986-1994)
- Erich B. Kusch (1995-2005)
- Prof. Dr. Elisabeth Kieven (2006-2012)
- Ambassador Michael H. Gerdts (2013-2020)
Former Italian Presidents:
- Ambassador Prof. Luigi Vittorio Ferraris (1989-2005)
- Ambassador Umberto Vattani (2006-2012)
- Ambassador Leonardo Visconti di Modrone (2013-2016)
Former Secretary Generals
- Paul Harro Piazolo (1987-1992)
- Prof. Dr. Rudolf Lill (1993-1996)
- Prof. Dr. Bernd Roeck (1997-1999)
- Prof. Dr. Aldo Venturelli (2000-2007)
- Prof. Dr. Gregor Vogt-Spira (2008 - 2012)
- Prof. Dr. Immacolata Amodeo (2012 - 2018)
